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Anal cancer rates and deaths on the rise in the US

Researchers have examined trends in anal cancer cases for about 15 years, during which time they have identified approximately 69,000 cases of anal cancer and more than 12,000 deaths.

Our findings regarding the increase in the incidence of black women and white women, the increase in distant disease rates and the increase in anal cancer mortality rates are very important. UTHealth Public Health School said in a statement. "Given the historical perception that anal cancer is rare, it is often neglected."

Distant stage disease is when cancer spreads to other parts of the body.

From 2001 to 2015, the most common anal cancer cases increased by 2.7% per year, while anal cancer mortality rates increased by 3.1% per year from 2001 to 2016.

"There is a trend that seems to have taken place in the last decade," the study published in the National Cancer Institute Journal. Said. “In this sense, he gives us what we expect.” Shaffer was not involved.

HPV-related cancer

Anal cancer occurs where the digestive system ends. It is different from colon or rectal cancer and most similar to cervical cancer.

The most common subtype of anal cancer is squamous cell carcinoma caused by human papilloma virus known as HPV.

According to the US Centers for Disease Control and Prevention, more than 90% of anal cancer cases are associated with HPV.
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Anal cancer screening was performed for some high-risk groups, but research authors argued that their findings were tarama more extensive screening efforts should be considered ". However, they believe that the increase in diagnostic practices will not be due to the increase in screening practices.
Since the 1950s, there have been significant changes in risk factors for anal cancer, including changes in sexual behavior and increased sexual partners, both of which increase the likelihood of developing HPV.
The emergence of an HIV epidemic may have affected anal cancer tendencies as HIV is a risk factor, especially among men who have sex with men.
There are other risk factors, such as having a cervical or vulvar cancer, having a transplant, or being a smoker.

Who was affected by anal cancer?

The study found that anal cancer cases increased significantly in people 50 years and older.

Because the HPV vaccine guidelines are "too narrow," Shaffer said he limits protection for older adults. Shaffer was approved for people aged 9 to 26 when the first HPV vaccine was given in 2006, "These older adults had already passed this cut when the vaccine was delivered," Shaffer said. “This is a large number of people who have missed the vaccination,” he said.
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Anal cancer rates are also increasing among young black males.

The study authors said that HIV also disproportionately affects young black men and that HIV is a risk factor for anal cancer.

The study also found that the number of advanced stage cases was increasing. This may be partly due to the improved HIV treatment, Shaffer said, meaning that patients live safely with the immune system for longer periods of time and make further progress when they are diagnosed with cancer.

Stop stain

There's still stigma around the anal cancer.

"Desperate Housewives" star Marcia Cross said it opened about anal cancer diagnosis earlier this year to help eradicate the disease.

"I know there are people who are ashamed," Cross said in June, "CBS This Morning." “You have cancer. Then you want to feel it? "You're ashamed that you did something bad because it resided in your anus."

Anal cancer has become “quite taboo, Sh Shaffer said, orum I think historically it is due to some known risk factors.

Insanlar If people are experiencing symptoms, they should see a doctor because I think a lot of people & # 39; Oh, it's just hemorrhoids. he thinks and doesn't take control of something, which means you won't recognize him very, very much. "

Anal cancer can be prevented by HPV vaccination. In the United States, the CDC recommends two doses of vaccines for children aged 11 to 12 years with an interval of one year. Young adults up to 26 years of age can also be vaccinated. Older adults should talk to their physician before a person is exposed to HPV because the vaccine is most useful when administered at a younger age.

To strengthen forward-looking prevention efforts, Shaffer said that all people who qualify for vaccination should do so, and that existing vaccine guidelines should be worked to determine if they can be extended to other patients.

Michael Nedelman from CNN, Lisa Respers France and Sandee LaMotte contributed to this report.

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