Wednesday , October 20 2021

Republic / SKANDAL! Half of Serbia is drinking anti-pressure medications that can cause cancer, be sure to check your skin.



In Serbia, the most commonly used medication is given to almost all patients with hypertension and hydrochlorothiazide, which can cause non-melanoma skin cancer. All healthcare workers in this country are given the latest warning from the Pharmaceutical and Medical Devices Agency (ALIMS), Blic .


At this senior Serbian medical institution, they recommended that patients using this drug monitor all changes in their skin and inform the doctor immediately if they notice abnormal occurrences.

Cardiologists say that this drug prescribes the rest of the treatment for the treatment of high blood pressure to remove excess fluid in the body. The drug belongs to the so-called diuretics resulting from the removal of excess fluid from the body by lowering blood pressure and reducing the isotope caused by the retention of this fluid.



According to the same data, the initial dose for hypertension is 12.5 milligrams and may gradually increase until the desired result is achieved. The latest statistics show that high blood pressure in Serbia is from about 47 per cent of the adult population, and that more than 50,000 people die every year from heart disease and blood vessels.

Due to such extensive use, the Agency issued a letter to health professionals on Tuesday along with the licensors on the risk of "non-melanoma skin cancer associated with the use of hydrochlorothiazide Bu.

They affirmed this in ALIMS for Blic, and in a statement to health workers, they said that pharmacoepidemiological studies showed an increased risk of non-melanoma skin cancer – basocellular and planocellular carcinoma when exposed to high cumulative doses of this drug.


Pressure indicator

– Patients on hydrochlorothiazide alone or in combination with other drugs should be informed about the risk of non-melanoma skin cancer and are advised to review the skin regularly due to possible development of new lesions, ie skin lesions or changes in existing lesions. Tell your doctor immediately about any suspected skin lesions – he says the ALIMS warning that Blic is insightful.


While informing health workers more, suspicious skin phenomena should be examined immediately and, if necessary, a sample of such a change may be taken for histological examination. In addition to doctors telling patients to limit their exposure to sunburn and UV rays, physicians should "carefully consider the use of hydrochlorothiazide in patients who have had skin cancer before."


Doctors should tell patients that they should limit their exposure to sunburn and UV rays.

ALIMS reminded doctors that medicines should report any side effects to pharmacovigilance or adverse drug reactions.


Professor Famous Serbian heart surgeon. Miljko Ristic says that this drug is widely used and given to those who are hypertensive.

– It is one of the classic drugs given for the treatment of hypertension in recent years or even longer. All medications used in the treatment of high blood pressure as well as other diseases have side effects. They are recorded regularly and their frequency is recorded. The obligation of the manufacturers is to inform users or patients about this. Depending on how much of the drug and what kind of side effects the drug can be withdrawn from use – prof. Miljko Ristić.

e-stock / M. Yoshida

Dr. Miljko Ristic


According to her, this drug cannot be used because it is still necessary to take medications used to remove fluid from the body in patients with hypertension.

– The Drug Office should inform citizens who are alternative medicines and are on the market – says prof. Ristic.

As he explained, it is a good thing that ALIMS calls healthcare professionals to report any suspicious cases during drug use because if skin cancer is detected over time, they can be treated.

– Patients with cardiovascular disease also have hypertension, because this is exactly the cause of these diseases. For years, we have been in the number of deaths from cardiovascular diseases in Europe. In Serbia, approximately 55 per cent of patients die from cardiovascular disease, while 45 per cent are caused by others – says prof. Ristic.


Ristic: Patients with cardiovascular disease also have hypertension, because this is exactly the cause of these diseases.

According to the EMA, the European Medicines Agency (EMA) assessed the available data sources of two recent pharmacoepidemiological studies with Danish national data sources, including the Danish Risk Assessment Committee, the Danish Malign Disease Record and the National Medical Recipe Record. Depending on the cumulative dose, there is a link between the use of hydrochlorothiazide and non-melanoma skin cancer.

One example is that a cumulative dose of 50,000 milligrams corresponds to a dose of 12.5 milligrams of hydrochlorothiazide administered over 11 years on a daily basis. And this is the first dose given to patients as indicated in the instructions for the drug.

Source link