Friday , September 24 2021

When COVID-19 patients are at risk of thrombosis – Rossiyskaya Gazeta



Why can blood clots form in postcoid patients? Who has a higher risk? So, is it possible to become a source of coronavirus for other people after vaccination? “RG” -Week experts continue to answer our readers’ questions.

Is it true that a person can be a carrier of coronavirus after being vaccinated and infect others?

If a person becomes ill with COVID-19 immediately after vaccination, it has nothing to do with the introduction of the vaccine. Most likely, he was already infected at the time of vaccination or even immediately afterwards, even before the development of protective antibodies. According to the Russian Ministry of Health, up to 2.5% of those vaccinated become ill with COVID-19, while the disease can progress as a mild ARVI or without symptoms. Such a person can actually spread the virus if he actively communicates with people without observing protective measures.

For example, it is no coincidence that the United States has introduced mandatory testing for COVID-19 for those vaccinated if they come into contact with sick people. In addition, they had to pass the analysis even in these cases if there were no symptoms of the disease. Such recommendations were issued by the CDC (US Centers for Disease Control and Prevention) based on new data that people can become infected with the coronavirus even after vaccination and remain carriers for a period of time and spread the infection.

CDC Director Dr. “Our updated guidelines recommend that vaccinated people be tested when exposed to an infection, regardless of whether they develop symptoms,” said Rochelle Walenski.

Additionally, the CDC has tightened its mask-wearing recommendations:

fully vaccinated persons should wear masks in public places (closed rooms) after contact with a sick person;

they should be tested for the virus three to five days after contact;

if test results are negative, they may stop wearing masks indoors;

If the test is positive, the coronavirus carrier must be isolated by staying at home for 10 days.

The new CDC solution builds on recent research that even fully vaccinated people infected with the delta strain can carry the virus and pass it on to others.

Why can a person with coronavirus have thrombosis?

According to the Russian Ministry of Health, this risk is quite high – a tendency to thrombosis is noted in every third postcoitus patients.

“One of the tropic cells favorable for the replication of the SARS-CoV-2 virus is the endothelium, which covers the inner surface of blood vessels,” explains the chief infectious disease physician. Clinical Diagnostics Laboratory “Invitro-Siberian” Andrey Pozdnyakov – Normally they are very flexible and blood moves between them without any barriers.

Because the endothelium is restored quite slowly, thrombosis can occur if the inner lining of the vessels is disrupted by the SARS-CoV-2 virus. In this case, the person may not suspect that they have developed a blood clot. “

Complications such as thrombosis are more common in whom?

“First of all, these are people with a genetic predisposition. It is quite common in this population, so there are many people who need to closely monitor the condition of their blood vessels,” says Andrey Pozdnyakov.

At the same time, it is impossible to decide whether there is a genetic predisposition, for example, whether the closest relatives suffer from thrombosis. Dr. “Absolutely any person can be a carrier of a hemostasis mutation and have a tendency to thrombosis. This can be detected using genetic testing, for example,” hemostasis mutations,” explained Dr. Pozdnyakov.

He also explained why it is necessary to take control of your condition by performing the necessary tests as recommended by the doctor. “This trend practically does not manifest itself in ordinary life. Unfortunately, in genetically predisposed people, the first detection is often fatal – it can be a stroke, heart attack or thrombosis of any other vessel,” Pozdnyakov said.

Coronavirus affects blood vessels, hence high risk of thrombosis

The doctor advised to be especially careful for people with endocrine diseases associated with impaired glucose metabolism, those who are overweight, chronic cardiovascular diseases – these categories have a higher risk of developing thrombosis. Traditionally, thrombosis in the “cores” is one of the most common complications, since almost all of them suffer from atherosclerosis of the vessels. If the integrity of the inner lining of the vessels is damaged, blood clots easily form on them. If already compromised people get sick with COVID-19, the risks of thrombosis are too great for them. That’s why COVID-19 is dangerous for people with cardiovascular and endocrine pathology, their blood clotting changes greatly, and they often die from thrombotic complications,” the doctor said.

Why are women often warned about the threat of thrombosis?

In some cases, it is worth checking blood coagulation indicators for healthy people. For example, younger women who take oral contraceptives are more likely to develop blood clots. Andrei Pozdnyakov, “Therefore, if there are problems with blood clots, it is better not to use birth control pills. You need to consult a doctor and switch to other methods of contraception.”

Can the vaccine increase the risk of thrombosis?

“Any vaccine is a stress reaction for the body, which, among other things, can carry an increased risk of thrombus formation. People with mutations in the hemostatic system may be susceptible to it,” Pozdnyakov said. Said.

As for the vaccine against COVID-19, in official sources Sputnik V does not have a risk of thrombosis.

At the same time, for example, in Germany, if an at-risk person was vaccinated with the first dose of AstraZeneca vaccine, it was decided to receive a second dose of Pfizer vaccines – precisely to reduce the risk of complications.


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