Researchers at the University of Göttingen, Germany have determined that motor nerve cells trigger nerve excitability, restless leg syndrome.
According to Dirk Czesni, "Restless Legs Syndrome mechanisms are still not fully understood." We have shown that the nerve cells that feed the muscles in his leg are responsible, "he says. Journal of Physiology This may offer a breakthrough in the treatment of RLS.
RLS is a common condition in which the nervous system causes an intolerable resistance to move the legs. Patients complain of unpleasant symptoms such as tingling, burning and painful cramping in the leg. More than 80% of people with RLS often tremble or twitch uncontrollably at night at night.
Until now, RLS has been thought to be caused by genetic, metabolic and central nervous system mechanisms. For the first time, researchers also show peripheral nerve cells that target not only the central nervous system but also the responsible muscles. Because of the increased excitability of nerve cells feeding the muscles of the leg, an increasing number of signals are sent between the nerve cells.
According to a research team from University of Sydney and University of Göttingen and Vanderbilt University, the way of sending messages between nerve cells to help reduce the number of messages to normal levels can help prevent RLS symptoms. This can be achieved by new drugs that block the ion channels necessary for communication between nerve cells. Tests are already in progress.