Colorectal cancer screening has not reduced mortality so far, but has reduced the need for chemotherapy and emergency surgery in male patients, showing a recent Finnish study.
Colorectal cancer is the third most common cancer in the world. In Finland, approximately 3,000 new cases are diagnosed each year and roughly 1,200 patients die. Between 2004 and 2016, a comprehensive screening program was conducted in Finland to investigate the potential benefits and adverse effects of a national-scale screening for colorectal cancer.
The study was aimed at individuals aged 60 edil69 years and half of the age group or half of the more than 300 thousand people were randomized at the end of 2011. Half of the population in the study was invited for screening and the other half served as the control group of the age group. Fecal occult blood tests (FOBT) were used for screening and patients who were positive for blood applied for colonoscopy.
The first study, based on screening results, showed no significant reduction in mortality, so scans were discontinued after 2016. However, researchers from the Helsinki University Hospital and the Finnish Cancer Register seek to examine whether the screening benefits patients with colorectal cancer. .
Uştur In practice, no cancer screening was found to have an impact on overall mortality. However, they can be useful in other ways. We wanted to investigate whether patients can be prevented from more intensive treatments if they participate in screening for colorectal cancer Kol. Dr. Laura Koskenvuo, gastrointestinal surgeon.
The data of approximately 1,400 patients with colorectal cancer were analyzed. The results showed that the surgical removal of the whole tumor was more successful among the patients in the screening group than in the control group, and the likelihood of needing chemotherapy was lower. Patients in the screening group were less likely to undergo less urgent surgery than their control group because of their tumors.
”The control group had 50% more emergency surgery, 40% more tumor absence and 20% more chemotherapy treatment.“ Ville Sallinen, gastrointestinal surgeon.
A closer examination of the results showed that these benefits were particularly prevalent among male patients. There were no similar benefits among women. In addition, investigators have found that screening is most effective in detecting left-sided colorectal cancer and that screening is not helpful for cancer patients on the right side; The column is no longer detectable by the gFOBT.
Esör The power of this Finnish study was to randomize a tremendous number of people in the public health system, which meant that we could objectively evaluate the benefits of screening. Nea Malila, Finnish Cancer Registry Manager.
Iy In the future, we should examine whether different screening techniques can improve the condition of female patients and facilitate the diagnosis of right-sided colorectal cancer, Araştırma the researchers said.