China, after a study that claimed that a scientist claimed in vitro fertilization with modified genes that led to HIV-resistant infants, initiated an experiment that was described as if dangerous, and ere irresponsible Çin.
O JiankuiAt the University of Shenzhen in South China, the professor published a video on YouTube that announced the birth of two twins a few weeks ago.
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After the Chinese scientists and institutions received many criticisms of this statement, the Chinese National Health Commission decided to açık investigate immediately birçok.
The researcher, who was trained in Stanford in the United States and operated a private laboratory in his genome in Shenzhen, said he was using the Crispr-Cas9 technique. "Genetic scissors"This allows the removal and modification of unwanted parts of the genome, and how to correct an error on a computer.
Babies called "Lula" and "Nana" were born by in vitro fertilization of a modified embryo before being implanted in the mother's womb. "Immediately after injecting your husband's sperm into the egg, an embryologist injected a Crispr-Cas9 protein responsible for changing a gene to protect the girls from a future HIV infection," Jiankui said.
Genetically altering a DNA may serve to prevent disease, but this practice is problematic because genetic modifications will be inherited by new generations and may include a new eugenic form.
MIT Technology Assessment, "technology has an ethical responsibility," he recalled.
The announcement of this medical trial made a statement at the beginning of the Chinese conference of genome specialists in Hong Kong that the Chinese researchers should present their results in detail. However, after criticism, Intervention at this genetic congress is not guaranteed.
This self-proclaimed medical experiment is not independently verified. The Chinese team did not publish the results in a scientific journal.
"Very problematic" application
After the announcement, many Chinese scientists and institutions criticized this experiment.
The University where he works She's stopped taking her pay since February and I thought it was based on modified genes "Violation and rules of the ethical rules of the Academy".
"This research was carried out outside the framework of the university," he said on Monday.
Hundreds of Chinese scientists published a joint statement criticizing the experiment and asking for legislative changes related to in vitro fertilization.
This medical experiment had been known for some time, but no scientist dared to use it because he was critical of this group of scientists who believed that "nobody can predict the indeterminate effect of these genetic changes" that he opened "the box of Pandora".
In addition, international researchers criticized the announcement via a video on YouTube.
Nicholas Evans, professor of philosophy at Lowell University in Massachusetts, USA, who works on bioethical issues, said: "It is a very problematic scientific practice to announce these results in a video on YouTube."
”This eliminates the control processes in which many scientific advances, such as peer review, have been stopped, AF he added.
Sarah Chan from the University of Edinburgh, referred to by the Center for Science Media, raises the issue of # serious ethical concerns Sarah.
"These allegations, apparently, are deliberately irresponsible to seek maximum disputes (…)."
That Jiankui did not respond to AFP's questions immediately.