Saturday , October 23 2021

Body fat levels due to breast cancer risk in postmenopausal women


Dr. Andrew Dannenberg, who has a normal body mass index in the body, doubled the risk of estrogen-dependent breast cancer in patients with normal body mass index, says Dr Andrew Dannenberg. Weill is the director of cancer prevention at Cornell Medicine in Sandra and Edward Meyer Cancer Center.
The American Cancer Society, estrogen-dependent cancers called ER-positive breast cancer in the study, occur when the receptor proteins in or on the cells bind to the estrogen hormone and are based on growth.
Researchers have worked on 3,460 American women, aged 50-79, who have had menopause. Dannenberg was part of the Women's Health Initiative and said that body composition was measured at the beginning of this program. 146 of these women developed ER-positive breast cancer and the researchers sought a relationship between excess body fat and the development of this cancer.

They found that 5 kilograms (11 pounds) of increase in whole body fat mass was associated with an increase of 35% in the risk of such breast cancer. A 5-kilogram increase in fat mass of the trunk was associated with a 56% increase in risk.

According to the study, the body oil "is defined by the fat in the trunk except the head and limbs".

The study also found that a 5-kilogram increase in whole-body fat mass was associated with a 28% increase in risk for invasive breast cancer spreading to the surrounding breast tissue. The same increase in body fat was attributed to a 46% increase in the risk of invasive breast cancer.

Dannenberg, "basic body mass, even if you have a normal body mass index, having too much body fat to increase the risk of breast cancer." Said.

The BMI of a person is calculated by a formula that includes height and weight; According to the study, a "normal" BMI is considered to be between 18.5 and 24.9.

The researchers also looked at blood data at the beginning of the Women's Health Initiative for other factors known to be involved in the development of breast cancer, such as the rise of insulin molecules.

The results emphasize the importance of research that differentiates the contribution of body size, body composition and metabolic profiles to breast cancer risk. Isabel Pimentel, Ana Elisa Lohmann and Pamela J. Goodwin, in addition to the study, wrote in an editorial.

Editorial authors state that other researchers are looking at the subject with different results and k these observations show that the components of metabolic health may contribute to the risk of breast cancer rather than the presence of a complete metabolic syndrome Editör.

How much does your obesity elevate your cancer risk?
A particular strength of Hoda Anton-Culver's research at the University of California, Irvine School of Medicine, was to analyze the position of fat levels on the body.

Anton-Culver, who was not involved in the study, said: Anton I think that the body mass is a good step to look at the BKE as an indicator of obesity to really look at a certain part of the body's fat concentration, Araştır he said.

Scientists knew there was a relationship between obesity and cancer, but Anton-Culver says the new research carries research beyond that general association.

Lar In summary, obesity is associated with breast cancer, but more specifically, obesity around the abdomen is more specific for this relationship, “he says.

Anton-Culver pointed out that although he thought the study was strong, he only looked at a particular cancer.

”As a result, I don't know if we can look at the same problems with other cancers, what will happen, whether they are specific to breast cancer?“ "We need to ask this question again, because obesity is a risk factor for other cancers."

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