Scientists at the University of California, Los Angeles, have discovered a mechanism by which cancer cells can digest glucose and gain the energy necessary for the survival and growth of tumors. In addition, the content of some molecules in which a precancerous condition can be established in cells.
Scientists have identified a molecule known as sodium glucose cotransporter 2 (SGLT2). It is a protein that is responsible for the transfer of glucose into the cell. Cancer cells need glucose to survive and grow. Therefore, another type of carrier protein known as glucose carriers (GLUT) is extremely important for them. Previous studies have shown that SGLT2 may play an important role in the development of certain cancers, including prostate and pancreas.
Positron emission tomography has now been used to determine the activity of various glucose carriers in lung cancer cells at certain stages of the disease. These cells revealed that there was a large amount of SGLT2. This newly emerging tumor suggests that it is provided with carbohydrates, rather than sodium-glucose infant carriers, instead of GLUT. In addition, the increased concentration of SGLT2 may be present prior to the onset of the tumor. This converts the sodium-glucose infant carrier into an effective marker for the detection of malignant tumor formation at an early stage of development.