Reporters Biology Available On November 8, he made an astonishing discovery that the number of calories people spend on their days has changed. In rest, people burn 10 percent more calories in the early morning and early hours than in the early morning hours.
The findings reinforce the important role of the circadian clock in the management of metabolism. They also help explain why irregularities in eating and sleeping programs make it more likely for people to gain weight because of shift work or other factors.
, It surprised us to do the same thing more than a day to do the same thing at a different time of the day, Kir says Kirsi-Marja, Brigham and the Department of Sleep and Circadian Disorders in Women and Harvard Medical School, the lead author of the article.
Apart from the activity, sleep-wake cycle, and the effects of the diet, in order to determine changes in the course of the day in the metabolism, the researchers studied seven people in a private laboratory with no clue about when it was outside. There was no clock, window, phone or internet. Participants had the time to go to bed and wake up. Every night, four hours later, three hours each day for four weeks, four hours in the west, the equivalent was set to the west.
"Because they made the equivalent of traveling the world every week, they couldn't catch the inside of their bodies, and so they were released at their own pace," says co-author Jeanne Duffy and Women's Hospital at the Department of Sleep and Circadian Disorders at Brigham. "This allowed us to measure the metabolic rate in different biological times of today."
Data showed that resting energy expenditure was the lowest in the circadian phase. The researchers identified as ~ 0 ° in response to immersion in core body temperature at late biological night. The energy expenditure was about 180 hours, in the circadian phase, about 12 hours later, in the biological afternoon and in the evening.
The researchers found that the respiratory regions reflecting the macro-nutrient use of the participants also changed according to the circadian phase. This measure was the lowest in the evenings and the highest of the biological morning.
Researchers, researchers, accelerated resting energy expenditure and fasting breathing coefficient in the first characterization of the circadian profile by offering the activity, sleep-wake cycle and the effects of the diet, he says.
Er It doesn't eat what we eat, but when we eat and rest, it affects how much energy we burn or what we store as fat, D says Duffy. "Regular habits such as eating and sleeping are very important for general health."
Duffy, Zitting and his colleagues will look at how the appetite and the body's response to food has changed with the time of day. They also investigate how sleep time, duration and sleep patterns affect these reactions.
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Kirsi-Marja Zitting et al., Human Resting Energy Expenditure Changes according to Circadian Phase, Biology Available (2018). DOI: 10.1016 / j.cub.2018.10.005