Friday , October 22 2021

They are testing the first contraceptive gel for men on shoulders



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The US National Institutes of Health (NIH, for the English abbreviation), launched a series of clinical trials of a new male contraceptive gel to assess the ability to prevent pregnancy, the organization's official website reported.

The gel formula was developed by the NIH NGO Population Council and the National Child Health and Human Development Institute Eunice Kennedy Shriver (NICHD).

"Many women cannot use hormonal contraception and male contraceptive methods are limited by vasectomy and condoms, ı said Diana Blithe, who is the head of the NICHD Contraceptive Development Program and one of the study's researchers. Safe, highly effective, and a reversible male contraception method would satisfy an important public health need, "he said.

According to the report, the new gel called NES / T progestin compound segesterone acetate combined with testosterone. It is applied to the back and shoulders. and absorbed through the skin. Scientists prevent the production of natural testosterone in Progestin testes, reducing sperm production to low or nonexistent levels. testosterone replacementon the other hand maintains normal sexual desire and other functions based on appropriate levels of the hormone in the blood.

Researchers plan to research some of them 420 pairs. Male volunteers should use the NES / T gel for a period of four to 12 weeks to determine if they are tolerating the product and not experiencing unacceptable side effects. If sperm levels are not reduced appropriately, they will continue to use the gel for up to 16 weeks.

After the sperm levels of the volunteer fall to a sufficient threshold for contraception, they will enter the activity phase and evaluate the ability of the formulation to prevent pregnancy. This phase will last for 52 weeks, where the double's single contraceptive method will become the new gel. Men will continue to be monitored by researchers until 24 weeks after the NES / T application period has ended.

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