If you are sick of a study, high blood pressure, consuming fish, seafood and making a primarily vegetarian diet can help reduce the symptoms of heart disease associated with hypertension.
Fish, seafood and vegetarian food intake, said researchers from Warsaw Medical University in Poland, increased the level of a compound called trimethylamine N-oxide (TMAO), which is known to enhance heart health.
The study showed that low-dose therapy with TMAO reduced heart thickening (heart fibrosis) and markers of heart failure in a hypertension model.
"In our study, it is stated that the plasma TMAO provides new evidence for the potential beneficial effect of a reasonable increase in pressure over the overloaded heart."
For the study published in the American Journal of Physiology – Heart and Circulatory Physiology, the researchers analyzed the effect of TMAO on mice that have a tendency to develop high blood pressure.
A group of hypertensive rats were given low-dose TMAO supplements in drinking water and another group was given plain water.
They were given TMAO treatment for 12 weeks or 56 weeks and evaluated for heart and kidney damage as well as high blood pressure.
The results showed that TMAO treatment did not affect the development of high blood pressure in any of the spontaneous hypertensive rats.
However, the condition of the compounded animals was better than expected even after less than one year of low-dose TMAO treatment.
In addition, a four to five fold increase in plasma TMAO does not have adverse effects on the circulatory system.
Unlike previous research, researchers have shown that TMAO increases blood plasma levels and the risk of heart disease after consumption of red meat and eggs.
"A fish-rich and vegetarian diet is seen to be associated with a much higher plasma TMAO than red meat and egg-rich diets considered to increase cardiovascular risk."
"However, further studies are needed to assess the impact of TMAO and TMA on the circulatory system."